What is medicines reconciliation?
Medicines reconciliation is the process of creating the most accurate and complete list possible of the medicines a person is taking and comparing that information with the medicines recorded or prescribed at a transfer of care.
The purpose is to identify and resolve discrepancies, reduce the risk of omitted or inappropriate treatment and make sure the current medicines record reflects the person’s actual treatment plan.
It is commonly completed when someone is admitted to hospital, moves between care settings, is discharged, enters a secure setting or joins a new service.
Why does medicines reconciliation matter?
Transfers of care create opportunities for information to be missed, delayed or misunderstood. A medicine may be omitted, duplicated, prescribed at the wrong strength or continued when it should have been stopped.
Good medicines reconciliation can help to:
- Reduce medicines-related harm.
- Prevent unintended omissions, duplications and dosing errors.
- Support continuity of treatment.
- Clarify intentional changes.
- Improve communication between care settings.
- Provide a reliable basis for prescribing and clinical review.
What information should be gathered?
The exact requirements vary locally, but a medicines reconciliation usually considers:
- Medicine name.
- Strength.
- Dose.
- Formulation.
- Route.
- Frequency and timing.
- Regular, when-required and recently stopped medicines.
- Allergies and adverse drug reactions.
- Over-the-counter, herbal and complementary products where relevant.
- Recent changes, monitoring requirements and supply arrangements.
The list should be clear enough for another professional to understand what the person is actually taking and what action is needed.
Use more than one source
No single source is always complete. Local policies often require information to be checked against more than one appropriate source.
Sources may include:
- The patient or their carer.
- GP or shared care records.
- Recent discharge letters or clinic correspondence.
- Community pharmacy records.
- Care home medicines administration records.
- Repeat medication lists.
- Medicine containers or monitored dosage systems.
- Specialist service information.
Each source has limitations. A repeat list may include medicines that are no longer taken, while a patient may remember a brand but not the strength. The task is to compare, clarify and document—not simply copy.
What is a discrepancy?
A discrepancy is a difference between the medicines a person was taking and the medicines currently recorded or prescribed.
Examples include:
- A medicine missing from the prescription.
- A medicine prescribed twice.
- A different strength or dose.
- An incorrect formulation or route.
- A medicine continued after it was intentionally stopped.
- A medicine stopped without a clear reason.
- An allergy or adverse reaction not recorded.
Some discrepancies are intentional. The important point is that the reason is clear, clinically appropriate and documented by the authorised professional.
A practical process
- Identify the patient correctly. Confirm the required identifiers before accessing or recording information.
- Collect information. Use the sources required by local policy.
- Build the current medicines list. Include complete details and relevant recent changes.
- Compare the list. Check it against the current prescription, chart or record.
- Identify discrepancies. Separate obvious documentation issues from matters requiring clinical review.
- Escalate appropriately. Refer concerns to the responsible pharmacist, prescriber or authorised clinician.
- Document clearly. Record sources, findings, actions, unresolved issues and who was informed.
- Close the loop. Confirm that agreed changes have been actioned where this sits within your role.
The pharmacy technician’s role
Trained and competent pharmacy technicians can make a major contribution to medicines reconciliation. Depending on the service, this may include gathering information, interviewing patients, comparing records, identifying discrepancies, documenting findings and escalating concerns.
The technician must understand:
- The local medicines reconciliation process.
- Which tasks they are authorised and competent to complete.
- Which findings require pharmacist or prescriber review.
- How to document sources and actions.
- How urgent or high-risk issues are escalated.
Questions that help during a patient conversation
Open questions can reveal information that is not visible on a medication list.
- “Can you talk me through the medicines you take on a normal day?”
- “Do you use any inhalers, creams, eye drops, injections or patches?”
- “Are there any medicines you take only when you need them?”
- “Have any medicines been started, stopped or changed recently?”
- “Do you buy any medicines, vitamins or herbal products yourself?”
- “Do you have any allergies or medicines that have caused a problem?”
- “Is there anything that makes it difficult to take your medicines?”
Use the terminology and questions approved by your organisation. Avoid leading the patient or suggesting an answer.
High-risk situations
Local prioritisation systems may identify patients or medicines that need rapid review. Examples can include anticoagulants, insulin, anti-epileptic medicines, immunosuppressants, clozapine, opioid substitution therapy and medicines with complex monitoring or dosing schedules.
Do not rely on a generic list alone. Follow the high-risk criteria and escalation process used by your service.
Common mistakes
- Copying a repeat list without confirming current use.
- Recording the medicine name but not the strength, formulation or dose.
- Forgetting non-oral medicines and when-required medicines.
- Assuming a discrepancy is intentional without checking.
- Failing to record the information sources used.
- Escalating the issue but not documenting the action.
- Working beyond competence or local authorisation.
Documentation
Accurate and timely documentation is part of clinical governance. Record the sources checked, the medicines information obtained, discrepancies identified, action taken, unresolved issues and the person to whom concerns were escalated.
Use the approved local system and follow confidentiality, audit trail and record-retention requirements.
Practical checklist
- Confirm the patient’s identity.
- Use the required number and type of information sources.
- Record medicine name, strength, form, route, dose and frequency.
- Check allergies and adverse reactions.
- Include recent changes and non-prescription products where relevant.
- Compare against the current chart or record.
- Escalate discrepancies through the correct route.
- Document sources, findings and actions clearly.
- Confirm follow-up where required by your role.
Pharmacy Technician Hub’s View
Medicines reconciliation is not a copying exercise. It is a structured patient-safety process that depends on accurate information, careful comparison, professional curiosity and clear escalation.
Pharmacy technicians can add significant value when they are properly trained, competent and supported by clear governance. The standard should always be an accurate medicines history that another professional can trust and act upon safely.
Official guidance
- NICE NG5: Medicines optimisation
- NICE QS120: Medicines reconciliation in acute settings
- NHS SPS: Clinical governance and patient safety records in pharmacy